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Those who receive two different Corona vaccines in their first and second vaccinations have an increased likelihood of mild and moderate side effects after the second dose. That’s according to data from an Oxford University study published in the journal The Lancet.
The study examined cases in which either the AstraZeneca preparation was administered first and then the Biontech/Pfizer vaccine, or vice versa, at intervals of four weeks. In both cases, the frequency of mild and moderate adverse events was increased. “The results of this study suggest that giving two different doses leads to increased absenteeism from work the day after vaccination,” said Matthew Snape of Oxford University, who led the study. That’s important, he said, for such things as scheduling vaccinations for health care workers.
The study looked at 830 volunteers over the age of 50, who were divided into four groups, each receiving two doses of the same type of vaccine in a different order, first one and then the other. It is possible that the side effects are even more common in younger people, the release added. In April, the study was expanded to include other variants with the Moderna and Novavax vaccines as a second dose after initial vaccination with AstraZeneca or Biontech/Pfizer – the results of which are still pending.
It is not yet possible to assess whether the immune response is affected. However, data on this would be expected in the coming months. However, the scientists emphasized that there is no reason to worry about patient safety.
- source: heute.at/picture: pixabay.com
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